Which side effects are commonly associated with bupropion?

Bupropion is an atypical antidepressant that is commonly prescribed for depression and smoking cessation. It operates primarily by inhibiting the reuptake of norepinephrine and dopamine, which contributes to its unique side effect profile compared to other antidepressants.

Among the commonly reported side effects, insomnia and agitation are significant. Bupropion often stimulates the central nervous system, leading to increased energy and the potential for insomnia, particularly if taken later in the day. Agitation can occur due to the stimulating effects of the medication, which may disturb sleep patterns and increase restlessness in some individuals.

QT prolongation, while less common than insomnia and agitation, can also occur in susceptible individuals or at higher doses. Monitoring is recommended, particularly in patients with a predisposition to cardiac issues.

In contrast, the other options correlate with different medication profiles. Weight gain and sedation are more typically associated with medications like SSRIs or certain mood stabilizers rather than bupropion, which is often noted for weight neutrality or even weight loss. Nausea and vomiting can occur but are not as prominent as the central nervous system-related side effects. Drowsiness and headache are not commonly cited as primary effects of bupropion. Therefore, the side effects