Which of the following is a characteristic of cystic fibrosis related to male reproductive health?

Bilateral absence of the vas deferens is a characteristic of cystic fibrosis that directly impacts male reproductive health. In individuals with cystic fibrosis, mutations in the CFTR gene lead to the production of thick, sticky mucus that can obstruct the vas deferens, resulting in its absence or significant abnormalities. This condition is known as congenital bilateral absence of the vas deferens (CBAVD), and it's a common cause of infertility in males with cystic fibrosis.

The absence of the vas deferens means that sperm cannot travel from the testes to the ejaculatory duct, leading to obstructive infertility. This condition highlights the importance of understanding the reproductive implications of cystic fibrosis in male patients, as they may require advanced reproductive technologies for conception, such as sperm retrieval techniques.

Other considerations, such as the bilateral absence of the epididymis, reduced sperm count, and low testosterone levels, are less directly associated with cystic fibrosis. While men with cystic fibrosis can experience fertility issues, the key reproductive characteristic related to the disease specifically pertains to the absence of the vas deferens. This demonstrates the unique intersection of cystic fibrosis and male reproductive health, emphasizing the critical need for healthcare providers to assess and address reproductive concerns in affected individuals.