Which medication class is known to cause esophageal irritation?

Tetracyclines are known to cause esophageal irritation, which is an important consideration when prescribing or instructing patients on their use. This class of antibiotics can sometimes lead to irritation and ulceration of the esophagus if not taken correctly. They should be taken with plenty of water and patients are typically advised to remain upright for at least 30 minutes after taking the medication to minimize the risk of irritation.

While aspirin can also cause gastrointestinal discomfort and has the potential to irritate the gastric lining, it is the tetracyclines that are more specifically associated with esophageal irritation. Statins and ACE inhibitors do not commonly cause esophageal irritation and are generally well-tolerated in that regard. Understanding the side effects of medications is crucial in the acute care setting, allowing for appropriate patient education and management.