What treatment has been shown to decrease morbidity and mortality in patients with COPD?

The treatment that has been shown to significantly decrease morbidity and mortality in patients with Chronic Obstructive Pulmonary Disease (COPD) is oxygen therapy. Chronic hypoxemia in COPD patients can lead to serious complications and a deterioration in the patient's overall health. Supplemental oxygen helps to maintain adequate oxygenation levels, which is crucial for preventing complications such as pulmonary hypertension and heart failure.

Oxygen therapy specifically benefits patients who have low oxygen saturation levels and are at risk for acute exacerbations. Long-term oxygen therapy has been linked to improved survival rates in patients with severe COPD and chronic respiratory failure, particularly when used in those with resting hypoxemia.

While other treatments like corticosteroids, antibiotics, and bronchodilators play important roles in managing COPD and alleviating symptoms, they do not specifically address the immediate need for replenishing oxygen levels in patients with chronic hypoxemia, which is the critical factor influencing morbidity and mortality in this population.