What symptom is associated with both acetaminophen and salicylate intoxication?

Nausea and vomiting are indeed associated with both acetaminophen and salicylate intoxication. In the context of acetaminophen overdose, the initial symptoms often include nausea and vomiting, along with other non-specific gastrointestinal symptoms. This can progress to more serious liver damage, but gastrointestinal distress is one of the early signs.

Similarly, salicylate toxicity, often seen with medications like aspirin, also presents with gastrointestinal symptoms, including nausea and vomiting. This is partly due to the irritation of the gastrointestinal tract caused by salicylates, as well as the body's response to metabolic acidosis and other systemic effects of the drug.

Both drugs can cause significant gastrointestinal symptoms, making nausea and vomiting common to both types of intoxication, and highlighting the importance of recognizing these signs in a clinical setting for the proper management of potential overdoses.