What symptom differentiates pericarditis from endocarditis?

Worsening pain with deep breathing is a hallmark symptom of pericarditis. This type of pain, often described as sharp or pleuritic, typically intensifies when a person takes a deep breath, coughs, or lies flat, due to irritation of the pericardium. The inflammation of the pericardium can lead to pain that changes with respiration, a feature not characteristic of endocarditis.

In contrast, endocarditis mainly presents with systemic symptoms such as fever, malaise, and may also include more specific signs like heart murmurs or evidence of embolic phenomena. While fever, malaise, night sweats, and weight loss are common symptoms across both conditions, they are not distinctive enough to differentiate between pericarditis and endocarditis. The generalized sick feeling could also apply to both conditions, making it less specific. Thus, the symptom of worsened pain with deep breathing serves as a key differentiator for pericarditis.