What is a possible complication of tertiary syphilis?

Tertiary syphilis can lead to various serious complications, one of which is cardiac insufficiency. This phase of syphilis can occur years after the initial infection if left untreated. The spirochetes can cause damage to the aorta, leading to a condition known as aortitis. This can result in an aneurysm or aortic regurgitation, promoting further cardiac complications, including heart failure and ultimately cardiac insufficiency.

Other options, such as skin rash, lymphadenopathy, and painful ulcers, are more typical of earlier stages of syphilis (primary and secondary syphilis). Tertiary syphilis is characterized by more severe systemic manifestations, particularly affecting the cardiovascular and central nervous systems.