What disease is associated with Heberden's nodes?

Heberden's nodes are bony growths that develop at the distal interphalangeal (DIP) joints of the fingers, and they are a characteristic feature of osteoarthritis. These nodes are indicative of the degenerative changes that occur in the joints due to osteoarthritis, which involves the breakdown of cartilage, leading to the formation of bone spurs and subsequent joint deformities.

In contrast, rheumatoid arthritis generally affects the proximal interphalangeal (PIP) joints and presents with symmetrical joint inflammation rather than bony growths at the DIP joints. Gout is characterized by acute episodes of inflammatory arthritis, particularly at the big toe, due to uric acid crystal deposition, without the formation of Heberden's nodes. Psoriatic arthritis can lead to various changes in the joints and is often accompanied by skin lesions, but it does not typically involve the formation of Heberden's nodes. Thus, the association of Heberden's nodes with osteoarthritis is well-documented, making it the correct answer.